In 1819, Queen Victoria was born with what scientists currently believe was a spontaneous mutation in her genome. Though unaffected herself, some of her children and then her grandchildren began to show signs of a bleeding disease. Her great-grandson, Alexei Romanov, would go on to seek the consultation of Grigori Rasputin to treat this condition. In time, the “royal disease” would go on to become one of the most famous examples of a hereditary disease, known more commonly today as hemophilia. However, it wasn’t until 1902 when Archibald Garrod’s observations of alkaptoneuria, highlighted the relevance of Mendel’s principles in the study of hereditary diseases (Urban, 1999). With today’s advancements in medicine, the focus naturally turns to conditions that are inherited, and whether or not a cure could ever be possible.